Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition

Nucleoplasmin (Npm) is an abundant histone chaperone in vertebrate oocytes and embryos.During embryogenesis, regulation of Npm histone binding is critical for its function in storing and releasing maternal histones to establish and maintain the zygotic epigenome.Here, we demonstrate that Xenopus laevis Npm post-translational modifications (PTMs) sp

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Ecological evolution of salmonids

For the first time, ecological evolution of salmonid fishes is analyzed using the method of historical biogeography, considering formation of ecology and reproductive biology for these species under planetary climatic and geological changes.Climate cooling in the Cenozoic and associated reconstruction of the food base for salmonids had a major impa

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